| Team | P | W | D | L | Pts |
| Leicester Tigers | 22 | 18 | 1 | 3 | 82 |
| London Wasps | 22 | 16 | 0 | 6 | 74 |
| Bath Rugby | 22 | 14 | 0 | 8 | 70 |
| Northampton Saints | 22 | 13 | 0 | 9 | 59 |
| Saracens | 22 | 12 | 0 | 10 | 58 |
| Newcastle Falcons | 22 | 11 | 0 | 11 | 57 |
| Gloucester Rugby | 22 | 10 | 0 | 12 | 48 |
| London Irish | 22 | 10 | 1 | 11 | 45 |
| Bristol Rugby | 22 | 9 | 1 | 12 | 44 |
| Sale Sharks | 22 | 8 | 1 | 13 | 43 |
| Harlequins | 22 | 7 | 0 | 15 | 38 |
| Rotherham Titans | 22 | 2 | 0 | 20 | 12 |
| Result Date | Team | Pts | Team | Pts | |||
| 19 Aug 2000 | Leicester Tigers | 4 | London Wasps | 1 | Table | Match | ||
| London Irish | 4 | Harlequins | 1 | Match | |||
| Sale Sharks | 4 | Bath Rugby | 1 | Match | |||
| 20 Aug 2000 | Newcastle Falcons | 4 | Northampton Saints | 1 | Table | Match | ||
| Bristol Rugby | 4 | Rotherham Titans | 1 | Match | |||
| Saracens | 5 | Gloucester Rugby | 0 | Match | |||
| 26 Aug 2000 | Saracens | 4 | Bristol Rugby | 0 | Table | Match | ||
| Sale Sharks | 4 | Gloucester Rugby | 1 | Match | |||
| Harlequins | 5 | Rotherham Titans | 0 | Match | |||
| Northampton Saints | 4 | London Irish | 0 | Match | |||
| 27 Aug 2000 | Leicester Tigers | 5 | Newcastle Falcons | 1 | Table | Match | ||
| Bath Rugby | 5 | London Wasps | 0 | Match | |||
| 2 Sep 2000 | Leicester Tigers | 4 | Northampton Saints | 0 | Table | Match | ||
| Bath Rugby | 5 | Harlequins | 0 | Match | |||
| London Irish | 4 | Saracens | 1 | Match | |||
| Gloucester Rugby | 5 | Rotherham Titans | 1 | Match | |||
| Newcastle Falcons | 4 | Sale Sharks | 0 | Match | |||
| 3 Sep 2000 | London Wasps | 4 | Bristol Rugby | 1 | Table | Match | ||
| 6 Sep 2000 | Sale Sharks | 4 | Bristol Rugby | 0 | Table | Match | ||
| Gloucester Rugby | 4 | Newcastle Falcons | 1 | Match | |||
| Northampton Saints | 4 | Harlequins | 1 | Match | |||
| Leicester Tigers | 5 | Rotherham Titans | 0 | Match | |||
| London Wasps | 4 | Saracens | 1 | Match | |||
| 9 Sep 2000 | Bath Rugby | 4 | Gloucester Rugby | 1 | Table | Match | ||
| London Wasps | 5 | Harlequins | 0 | Match | |||
| Sale Sharks | 5 | Northampton Saints | 0 | Match | |||
| 10 Sep 2000 | Newcastle Falcons | 5 | Rotherham Titans | 0 | Table | Match | ||
| London Irish | 4 | Bristol Rugby | 1 | Match | |||
| Saracens | 4 | Leicester Tigers | 0 | Match | |||
| 16 Sep 2000 | Bath Rugby | 4 | Newcastle Falcons | 1 | Table | Match | ||
| Harlequins | 4 | Bristol Rugby | 1 | Match | |||
| Leicester Tigers | 5 | London Irish | 0 | Match | |||
| Northampton Saints | 5 | Rotherham Titans | 0 | Match | |||
| Saracens | 5 | Sale Sharks | 0 | Match | |||
| 17 Sep 2000 | London Wasps | 5 | Gloucester Rugby | 0 | Table | Match | ||
| 23 Sep 2000 | Newcastle Falcons | 5 | London Wasps | 0 | Table | Match | ||
| Bristol Rugby | 4 | Leicester Tigers | 1 | Match | |||
| Gloucester Rugby | 4 | Harlequins | 1 | Match | |||
| Northampton Saints | 4 | Bath Rugby | 0 | Match | |||
| 24 Sep 2000 | London Irish | 4 | Sale Sharks | 0 | Table | Match | ||
| Saracens | 5 | Rotherham Titans | 0 | Match | |||
| 30 Sep 2000 | Saracens | 4 | Bath Rugby | 0 | Table | Match | ||
| Gloucester Rugby | 5 | Bristol Rugby | 0 | Match | |||
| Newcastle Falcons | 4 | Harlequins | 1 | Match | |||
| Rotherham Titans | 4 | London Irish | 1 | Match | |||
| Sale Sharks | 2 | Leicester Tigers | 2 | Match | |||
| 1 Oct 2000 | London Wasps | 5 | Northampton Saints | 0 | Table | Match | ||
| 18 Nov 2000 | Bristol Rugby | 4 | Rotherham Titans | 0 | Table | Match | ||
| Gloucester Rugby | 4 | Saracens | 1 | Match | |||
| Leicester Tigers | 4 | London Wasps | 0 | Match | |||
| Northampton Saints | 4 | Newcastle Falcons | 0 | Match | |||
| 19 Nov 2000 | Bath Rugby | 4 | Sale Sharks | 2 | Table | Match | ||
| London Irish | 4 | Harlequins | 1 | Match | |||
| 24 Nov 2000 | Leicester Tigers | 4 | Harlequins | 1 | Table | Match | ||
| 25 Nov 2000 | Gloucester Rugby | 4 | London Irish | 0 | Table | Match | ||
| Northampton Saints | 4 | Bristol Rugby | 0 | Match | |||
| 26 Nov 2000 | Bath Rugby | 5 | Rotherham Titans | 0 | Table | Match | ||
| Newcastle Falcons | 4 | Saracens | 1 | Match | |||
| London Wasps | 4 | Sale Sharks | 0 | Match | |||
| 2 Dec 2000 | Bristol Rugby | 4 | Bath Rugby | 1 | Table | Match | ||
| Leicester Tigers | 4 | Gloucester Rugby | 1 | Match | |||
| London Wasps | 4 | Rotherham Titans | 0 | Match | |||
| Sale Sharks | 5 | Harlequins | 0 | Match | |||
| 3 Dec 2000 | Northampton Saints | 4 | Saracens | 0 | Table | Match | ||
| 5 Dec 2000 | London Irish | 4 | Newcastle Falcons | 1 | Table | Match | ||
| 16 Dec 2000 | Northampton Saints | 4 | Gloucester Rugby | 0 | Table | Match | ||
| Leicester Tigers | 4 | Bath Rugby | 0 | Match | |||
| London Irish | 4 | London Wasps | 1 | Match | |||
| Sale Sharks | 5 | Rotherham Titans | 0 | Match | |||
| 17 Dec 2000 | Bristol Rugby | 4 | Newcastle Falcons | 0 | Table | Match | ||
| Saracens | 4 | Harlequins | 0 | Match | |||
| 23 Dec 2000 | Bristol Rugby | 4 | Sale Sharks | 1 | Table | Match | ||
| Bath Rugby | 5 | London Irish | 0 | Match | |||
| Leicester Tigers | 4 | Rotherham Titans | 0 | Match | |||
| Gloucester Rugby | 4 | Newcastle Falcons | 0 | Match | |||
| London Wasps | 4 | Saracens | 0 | Match | |||
| Northampton Saints | 5 | Harlequins | 0 | Match | |||
| 26 Dec 2000 | Leicester Tigers | 4 | Bath Rugby | 1 | Table | Match | ||
| 27 Dec 2000 | Newcastle Falcons | 4 | Bristol Rugby | 0 | Table | Match | ||
| Saracens | 5 | Harlequins | 0 | Match | |||
| Northampton Saints | 4 | Gloucester Rugby | 1 | Match | |||
| London Wasps | 4 | London Irish | 0 | Match | |||
| 30 Dec 2000 | London Wasps | 4 | Northampton Saints | 1 | Table | Match | ||
| Bath Rugby | 5 | Saracens | 0 | Match | |||
| 6 Jan 2001 | Bath Rugby | 5 | Northampton Saints | 0 | Table | Match | ||
| Rotherham Titans | 4 | Saracens | 0 | Match | |||
| Bristol Rugby | 4 | Gloucester Rugby | 0 | Match | |||
| 6 Feb 2001 | Leicester Tigers | 4 | Bristol Rugby | 1 | Table | Match | ||
| Harlequins | 4 | Gloucester Rugby | 1 | Match | |||
| 10 Feb 2001 | Northampton Saints | 5 | Rotherham Titans | 0 | Table | Match | ||
| London Wasps | 4 | Gloucester Rugby | 0 | Match | |||
| Leicester Tigers | 5 | London Irish | 0 | Match | |||
| 11 Feb 2001 | Newcastle Falcons | 5 | Bath Rugby | 1 | Table | Match | ||
| Bristol Rugby | 4 | Harlequins | 1 | Match | |||
| Saracens | 5 | Sale Sharks | 0 | Match | |||
| 20 Feb 2001 | London Irish | 5 | Rotherham Titans | 0 | Table | Match | ||
| 24 Feb 2001 | Bath Rugby | 5 | Gloucester Rugby | 0 | Table | Match | ||
| Leicester Tigers | 5 | Saracens | 0 | Match | |||
| London Irish | 2 | Bristol Rugby | 2 | Match | |||
| Northampton Saints | 4 | Sale Sharks | 1 | Match | |||
| 6 Mar 2001 | Harlequins | 4 | Newcastle Falcons | 1 | Table | Match | ||
| Leicester Tigers | 4 | Sale Sharks | 0 | Match | |||
| 10 Mar 2001 | Leicester Tigers | 4 | Northampton Saints | 1 | Table | Match | ||
| Gloucester Rugby | 5 | Rotherham Titans | 0 | Match | |||
| Harlequins | 4 | Bath Rugby | 1 | Match | |||
| 11 Mar 2001 | Newcastle Falcons | 5 | Sale Sharks | 0 | Table | Match | ||
| London Wasps | 4 | Bristol Rugby | 0 | Match | |||
| Saracens | 5 | London Irish | 0 | Match | |||
| 14 Mar 2001 | Bath Rugby | 5 | London Irish | 0 | Table | Match | ||
| 17 Mar 2001 | Leicester Tigers | 5 | Newcastle Falcons | 0 | Table | Match | ||
| Bath Rugby | 4 | London Wasps | 1 | Match | |||
| Harlequins | 5 | Rotherham Titans | 0 | Match | |||
| London Irish | 4 | Northampton Saints | 1 | Match | |||
| Gloucester Rugby | 4 | Sale Sharks | 0 | Match | |||
| 18 Mar 2001 | Saracens | 4 | Bristol Rugby | 0 | Table | Match | ||
| 24 Mar 2001 | Sale Sharks | 5 | Rotherham Titans | 0 | Table | Match | ||
| 28 Mar 2001 | London Wasps | 5 | Newcastle Falcons | 0 | Table | Match | ||
| 31 Mar 2001 | Bath Rugby | 4 | Bristol Rugby | 1 | Table | Match | ||
| Gloucester Rugby | 4 | Leicester Tigers | 0 | Match | |||
| Harlequins | 5 | Sale Sharks | 0 | Match | |||
| Northampton Saints | 4 | Saracens | 0 | Match | |||
| 1 Apr 2001 | Newcastle Falcons | 5 | London Irish | 1 | Table | Match | ||
| London Wasps | 5 | Rotherham Titans | 0 | Match | |||
| 10 Apr 2001 | Newcastle Falcons | 5 | Rotherham Titans | 2 | Table | Match | ||
| Sale Sharks | 5 | London Irish | 0 | Match | |||
| London Wasps | 5 | Harlequins | 0 | Match | |||
| 14 Apr 2001 | London Wasps | 5 | Sale Sharks | 0 | Table | Match | ||
| Leicester Tigers | 5 | Harlequins | 0 | Match | |||
| Bath Rugby | 5 | Rotherham Titans | 0 | Match | |||
| 15 Apr 2001 | Saracens | 4 | Newcastle Falcons | 2 | Table | Match | ||
| 16 Apr 2001 | Bristol Rugby | 5 | Northampton Saints | 0 | Table | Match | ||
| London Irish | 4 | Gloucester Rugby | 0 | Match |
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