| Team | P | W | D | L | Pts |
| Leicester Tigers | 22 | 18 | 1 | 3 | 51 |
| Bath Rugby | 22 | 15 | 2 | 5 | 43 |
| Gloucester Rugby | 22 | 15 | 0 | 7 | 40 |
| Saracens | 22 | 14 | 0 | 8 | 37 |
| Northampton Saints | 22 | 13 | 0 | 9 | 35 |
| Bristol Rugby | 22 | 12 | 1 | 9 | 34 |
| London Wasps | 22 | 11 | 1 | 10 | 31 |
| London Irish | 22 | 9 | 1 | 12 | 25 |
| Newcastle Falcons | 22 | 6 | 2 | 14 | 19 |
| Harlequins | 22 | 7 | 0 | 15 | 18 |
| Sale Sharks | 22 | 7 | 0 | 15 | 18 |
| Bedford Blues | 22 | 1 | 0 | 21 | 3 |
| Result Date | Team | Pts | Team | Pts | |||
| 10 Sep 1999 | Bristol Rugby | 2 | Bedford Blues | 0 | Table | Match | ||
| 11 Sep 1999 | Gloucester Rugby | 2 | Newcastle Falcons | 0 | Table | Match | ||
| Bath Rugby | 2 | Harlequins | 0 | Match | |||
| Sale Sharks | 2 | London Wasps | 0 | Match | |||
| Northampton Saints | 2 | Leicester Tigers | 0 | Match | |||
| 12 Sep 1999 | London Irish | 2 | Saracens | 0 | Table | Match | ||
| 25 Sep 1999 | Bath Rugby | 2 | Northampton Saints | 0 | Table | Match | ||
| London Irish | 2 | Bedford Blues | 0 | Match | |||
| Harlequins | 2 | Saracens | 0 | Match | |||
| Leicester Tigers | 2 | Sale Sharks | 0 | Match | |||
| 26 Sep 1999 | London Wasps | 2 | Gloucester Rugby | 0 | Table | Match | ||
| Bristol Rugby | 2 | Newcastle Falcons | 0 | Match | |||
| 1 Oct 1999 | Gloucester Rugby | 2 | Leicester Tigers | 0 | Table | Match | ||
| Bristol Rugby | 2 | London Wasps | 0 | Match | |||
| Saracens | 2 | Bedford Blues | 0 | Match | |||
| 2 Oct 1999 | Sale Sharks | 2 | Bath Rugby | 0 | Table | Match | ||
| Northampton Saints | 2 | Harlequins | 0 | Match | |||
| 3 Oct 1999 | London Irish | 2 | Newcastle Falcons | 0 | Table | Match | ||
| 9 Oct 1999 | Saracens | 2 | Northampton Saints | 0 | Table | Match | ||
| 10 Oct 1999 | Sale Sharks | 2 | Harlequins | 0 | Table | Match | ||
| London Wasps | 2 | London Irish | 0 | Match | |||
| Bath Rugby | 2 | Gloucester Rugby | 0 | Match | |||
| 15 Oct 1999 | Gloucester Rugby | 2 | Harlequins | 0 | Table | Match | ||
| 16 Oct 1999 | Bristol Rugby | 1 | Bath Rugby | 1 | Table | Match | ||
| Leicester Tigers | 2 | London Irish | 0 | Match | |||
| 17 Oct 1999 | Northampton Saints | 2 | Sale Sharks | 0 | Table | Match | ||
| Saracens | 2 | Newcastle Falcons | 0 | Match | |||
| 23 Oct 1999 | Leicester Tigers | 2 | Bristol Rugby | 0 | Table | Match | ||
| 28 Oct 1999 | Harlequins | 2 | Bristol Rugby | 0 | Table | Match | ||
| 29 Oct 1999 | Saracens | 2 | Sale Sharks | 0 | Table | Match | ||
| 30 Oct 1999 | Bath Rugby | 1 | London Irish | 1 | Table | Match | ||
| Leicester Tigers | 2 | Bedford Blues | 0 | Match | |||
| Gloucester Rugby | 2 | Northampton Saints | 0 | Match | |||
| London Wasps | 1 | Newcastle Falcons | 1 | Match | |||
| 5 Nov 1999 | Gloucester Rugby | 2 | Sale Sharks | 0 | Table | Match | ||
| Newcastle Falcons | 1 | Leicester Tigers | 1 | Match | |||
| Northampton Saints | 2 | Bristol Rugby | 0 | Match | |||
| 6 Nov 1999 | Bath Rugby | 2 | Bedford Blues | 0 | Table | Match | ||
| 7 Nov 1999 | Saracens | 2 | London Wasps | 0 | Table | Match | ||
| Harlequins | 2 | London Irish | 0 | Match | |||
| 13 Nov 1999 | Bath Rugby | 3 | Newcastle Falcons | 0 | Table | Match | ||
| Harlequins | 3 | Bedford Blues | 0 | Match | |||
| Leicester Tigers | 3 | London Wasps | 0 | Match | |||
| Northampton Saints | 3 | London Irish | 0 | Match | |||
| Bristol Rugby | 3 | Sale Sharks | 0 | Match | |||
| 14 Nov 1999 | Gloucester Rugby | 3 | Saracens | 0 | Table | Match | ||
| 4 Dec 1999 | Northampton Saints | 3 | Bedford Blues | 0 | Table | Match | ||
| Gloucester Rugby | 3 | Bristol Rugby | 0 | Match | |||
| London Irish | 3 | Sale Sharks | 0 | Match | |||
| 5 Dec 1999 | London Wasps | 3 | Bath Rugby | 0 | Table | Match | ||
| Harlequins | 3 | Newcastle Falcons | 0 | Match | |||
| Saracens | 3 | Leicester Tigers | 0 | Match | |||
| 23 Dec 1999 | London Wasps | 3 | Harlequins | 0 | Table | Match | ||
| 26 Dec 1999 | Leicester Tigers | 3 | Bath Rugby | 0 | Table | Match | ||
| Gloucester Rugby | 3 | London Irish | 0 | Match | |||
| Sale Sharks | 3 | Bedford Blues | 0 | Match | |||
| Northampton Saints | 3 | Newcastle Falcons | 0 | Match | |||
| 27 Dec 1999 | Bristol Rugby | 3 | Saracens | 0 | Table | Match | ||
| 29 Dec 1999 | Leicester Tigers | 3 | Harlequins | 0 | Table | Match | ||
| London Irish | 3 | Bristol Rugby | 0 | Match | |||
| Newcastle Falcons | 3 | Sale Sharks | 0 | Match | |||
| Northampton Saints | 3 | London Wasps | 0 | Match | |||
| 30 Dec 1999 | Gloucester Rugby | 3 | Bedford Blues | 0 | Table | Match | ||
| Saracens | 3 | Bath Rugby | 0 | Match | |||
| 22 Jan 2000 | Gloucester Rugby | 3 | Bristol Rugby | 0 | Table | Match | ||
| Bath Rugby | 3 | London Wasps | 0 | Match | |||
| Newcastle Falcons | 3 | Harlequins | 0 | Match | |||
| Leicester Tigers | 3 | Saracens | 0 | Match | |||
| Northampton Saints | 3 | Bedford Blues | 0 | Match | |||
| 23 Jan 2000 | London Irish | 3 | Sale Sharks | 0 | Table | Match | ||
| 25 Jan 2000 | Harlequins | 3 | Bedford Blues | 0 | Table | Match | ||
| Bath Rugby | 3 | Newcastle Falcons | 0 | Match | |||
| Saracens | 3 | Gloucester Rugby | 0 | Match | |||
| Leicester Tigers | 3 | London Wasps | 0 | Match | |||
| 26 Jan 2000 | Northampton Saints | 3 | London Irish | 0 | Table | Match | ||
| 12 Feb 2000 | Bristol Rugby | 3 | Northampton Saints | 0 | Table | Match | ||
| Bath Rugby | 3 | Bedford Blues | 0 | Match | |||
| London Irish | 3 | Harlequins | 0 | Match | |||
| Leicester Tigers | 3 | Newcastle Falcons | 0 | Match | |||
| Gloucester Rugby | 3 | Sale Sharks | 0 | Match | |||
| 13 Feb 2000 | London Wasps | 3 | Saracens | 0 | Table | Match | ||
| 27 Feb 2000 | Newcastle Falcons | 2 | Bedford Blues | 0 | Table | Match | ||
| 8 Mar 2000 | Bristol Rugby | 3 | Sale Sharks | 0 | Table | Match | ||
| 11 Mar 2000 | Northampton Saints | 3 | Gloucester Rugby | 0 | Table | Match | ||
| Leicester Tigers | 3 | Bedford Blues | 0 | Match | |||
| Bristol Rugby | 3 | Harlequins | 0 | Match | |||
| Bath Rugby | 3 | London Irish | 0 | Match | |||
| 12 Mar 2000 | London Wasps | 3 | Newcastle Falcons | 0 | Table | Match | ||
| Saracens | 3 | Sale Sharks | 0 | Match | |||
| 25 Mar 2000 | Bath Rugby | 3 | Bristol Rugby | 0 | Table | Match | ||
| Gloucester Rugby | 3 | Harlequins | 0 | Match | |||
| Leicester Tigers | 3 | London Irish | 0 | Match | |||
| Northampton Saints | 3 | Sale Sharks | 0 | Match | |||
| 26 Mar 2000 | London Wasps | 3 | Bedford Blues | 0 | Table | Match | ||
| Newcastle Falcons | 3 | Saracens | 0 | Match | |||
| 8 Apr 2000 | Bedford Blues | 3 | Newcastle Falcons | 0 | Table | Match | ||
| Bath Rugby | 3 | Gloucester Rugby | 0 | Match | |||
| Sale Sharks | 3 | Harlequins | 0 | Match | |||
| 15 Apr 2000 | Bath Rugby | 3 | Sale Sharks | 0 | Table | Match | ||
| 16 Apr 2000 | Saracens | 3 | Bedford Blues | 0 | Table | Match | ||
| 18 Apr 2000 | Newcastle Falcons | 3 | London Irish | 0 | Table | Match | ||
| Leicester Tigers | 3 | Gloucester Rugby | 0 | Match | |||
| 19 Apr 2000 | Harlequins | 3 | Northampton Saints | 0 | Table | Match | ||
| Bristol Rugby | 3 | London Wasps | 0 | Match | |||
| 22 Apr 2000 | Gloucester Rugby | 3 | London Wasps | 0 | Table | Match | ||
| London Irish | 3 | Bedford Blues | 0 | Match | |||
| Leicester Tigers | 3 | Sale Sharks | 0 | Match | |||
| Bath Rugby | 3 | Northampton Saints | 0 | Match | |||
| 23 Apr 2000 | Bristol Rugby | 3 | Newcastle Falcons | 0 | Table | Match | ||
| 24 Apr 2000 | Saracens | 3 | Harlequins | 0 | Table | Match | ||
| 26 Apr 2000 | London Wasps | 2 | Bedford Blues | 0 | Table | Match | ||
| 29 Apr 2000 | Bath Rugby | 3 | Harlequins | 0 | Table | Match | ||
| Bristol Rugby | 3 | Bedford Blues | 0 | Match | |||
| Leicester Tigers | 3 | Northampton Saints | 0 | Match | |||
| Saracens | 3 | London Irish | 0 | Match | |||
| 30 Apr 2000 | London Wasps | 3 | Sale Sharks | 0 | Table | Match | ||
| Newcastle Falcons | 3 | Gloucester Rugby | 0 | Match | |||
| 6 May 2000 | Bath Rugby | 3 | Saracens | 0 | Table | Match | ||
| Gloucester Rugby | 3 | Bedford Blues | 0 | Match | |||
| Leicester Tigers | 3 | Harlequins | 0 | Match | |||
| Sale Sharks | 3 | Newcastle Falcons | 0 | Match | |||
| 9 May 2000 | London Wasps | 3 | Northampton Saints | 0 | Table | Match | ||
| 10 May 2000 | Bristol Rugby | 3 | London Irish | 0 | Table | Match | ||
| 14 May 2000 | Leicester Tigers | 3 | Bristol Rugby | 0 | Table | Match | ||
| Sale Sharks | 3 | Bedford Blues | 0 | Match | |||
| 17 May 2000 | London Irish | 3 | London Wasps | 0 | Table | Match | ||
| Saracens | 3 | Northampton Saints | 0 | Match | |||
| 20 May 2000 | Gloucester Rugby | 3 | London Irish | 0 | Table | Match | ||
| 21 May 2000 | Leicester Tigers | 3 | Bath Rugby | 0 | Table | Match | ||
| London Wasps | 3 | Harlequins | 0 | Match | |||
| Northampton Saints | 3 | Newcastle Falcons | 0 | Match | |||
| Saracens | 3 | Bristol Rugby | 0 | Match |
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